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. 2005 Jan 1;33(Database issue):D279-83.
doi: 10.1093/nar/gki016.

PFD: a database for the investigation of protein folding kinetics and stability

Kate F Fulton  1 , Glyn L Devlin, Rachel A Jodun, Linda Silvestri, Stephen P Bottomley, Alan R Fersht, Ashley M Buckle
Affiliations

PFD: a database for the investigation of protein folding kinetics and stability

Kate F Fulton et al. Nucleic Acids Res. .

Abstract

We have developed a new database that collects all protein folding data into a single, easily accessible public resource. The Protein Folding Database (PFD) contains annotated structural, methodological, kinetic and thermodynamic data for more than 50 proteins, from 39 families. A user-friendly web interface has been developed that allows powerful searching, browsing and information retrieval, whilst providing links to other protein databases. The database structure allows visualization of folding data in a useful and novel way, with a long-term aim of facilitating data mining and bioinformatics approaches. PFD can be accessed freely at http://pfd.med.monash.edu.au.

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Figures

Figure 1
Figure 1
The web-query interface to PFD. The database can be searched using multiple parameters relating to structural, thermodynamic and kinetic attributes.
Figure 2
Figure 2
A typical results page listing is shown. This is a summarized table, containing most of the important folding data. However, by clicking ‘Inspect’ you can show all the available folding data. This will also provide the link to the publication details.
Figure 3
Figure 3
The full entry can be retrieved for individual records, and hyperlinks allow efficient browsing (e.g. by SCOP family, molecularity, etc.).
See this image and copyright information in PMC

References

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Publication types