Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2005 Jan 1;33(Database issue):D523-6.
doi: 10.1093/nar/gki032.

IPD--the Immuno Polymorphism Database

James Robinson  1 , Matthew J Waller, Peter Stoehr, Steven G E Marsh
Affiliations

IPD--the Immuno Polymorphism Database

James Robinson et al. Nucleic Acids Res. .

Abstract

The Immuno Polymorphism Database (IPD) (http://www.ebi.ac.uk/ipd/) is a set of specialist databases related to the study of polymorphic genes in the immune system. IPD currently consists of four databases: IPD-KIR, contains the allelic sequences of Killer-cell Immunoglobulin-like Receptors; IPD-MHC, a database of sequences of the Major Histocompatibility Complex of different species; IPD-HPA, alloantigens expressed only on platelets; and IPD-ESTAB, which provides access to the European Searchable Tumour Cell-Line Database, a cell bank of immunologically characterized melanoma cell lines. The IPD project works with specialist groups or nomenclature committees who provide and curate individual sections before they are submitted to IPD for online publication. The IPD project stores all the data in a set of related databases. Those sections with similar data, such as IPD-KIR and IPD-MHC share the same database structure. The sharing of a common database structure makes it easier to implement common tools for data submission and retrieval. The data are currently available online from the website and ftp directory; files will also be made available in different formats to download from the website and ftp server. The data will also be included in SRS, BLAST and FASTA search engines at the European Bioinformatics Institute.

PubMed Disclaimer

Figures

Figure 1
Figure 1
The alignment interface provides a user-friendly method of viewing sequence alignments with output options easily selected.
Figure 2
Figure 2
Alignment formats available from IPD. The examples shown are all alignments of DRB alleles from different species. In these alignments a dash (-) indicates identity to the reference sequence and an asterisk (*) denotes an unsequenced base. The first alignment shows the nucleotide sequence of Chimpanzee (Pan troglodytes) DRB1 alleles with the human HLA-DRB1*010101 allele. The nucleotide sequence is also displayed in amino acid codons; the first base of the initial codon is encoded in exon 1 and so not displayed in this alignment. The second set of sequences shows DRB alleles from cattle. The final alignment uses canine DRB alleles, and demonstrates how the full sequence can be displayed.
See this image and copyright information in PMC

References

    1. Garcia C.A., Robinson,J., Guethlein,L.A., Parham,P., Madrigal,J.A. and Marsh,S.G.E. (2003) Human KIR sequences 2003. Immunogenetics, 55, 227–239. - PubMed
    1. Marsh S.G.E., Parham,P., Dupont,B., Geraghty,D.E., Trowsdale,J., Middleton,D., Vilches,C., Carrington,M., Witt,C., Guethlein,L.A. et al. (2003) Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002. Immunogenetics, 55, 220–226. - PubMed
    1. Kanz C., Aldebert,P., Althorpe,N., Baker,W., Baldwin,A., Bates,K., Browne,P., van den Broek,A., Castro,M., Cochrane,G. et al. (2005) The EMBL Nucleotide Sequence Database. Nucleic Acids Res., 33, D29–D33. - PMC - PubMed
    1. Benson D.A., Karsch-Mizrachi,I., Lipman,D.J., Ostell,J. and Wheeler,D.L. (2005) GenBank. Nucleic Acids Res., 33, D34–D38. - PMC - PubMed
    1. Miyazaki S., Sugawara,H., Ikeo,K., Gojobori,T. and Tateno,Y. (2004) DDBJ in the stream of various biological data. Nucleic Acids Res., 32, D31–D34. - PMC - PubMed