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. 1992 Feb;23(2):171-4.
doi: 10.1161/01.str.23.2.171.

Course of carotid artery occlusions with impaired cerebrovascular reactivity

B Kleiser  1 , B Widder
Affiliations

Course of carotid artery occlusions with impaired cerebrovascular reactivity

B Kleiser et al. Stroke. 1992 Feb.

Abstract

Background and purpose: Retrospective studies have found a close correlation between an impaired cerebrovascular reserve capacity and the incidence of hemodynamic stroke. The present study evaluates this relation prospectively.

Methods: We measured the CO2 reactivity in 85 patients with internal carotid artery occlusions by transcranial Doppler sonography (Doppler CO2 test). All patients were prospectively followed for 38 +/- 15 (mean +/- SD) months.

Results: In the group with sufficient CO2 reactivity, four of 48 (8%) developed ipsilateral transient symptoms, none a stroke. In cases with diminished or exhausted cerebrovascular reserve capacity, 12 of 37 (32%) suffered an ipsilateral event (four transient ischemic attacks, eight strokes) (p less than 0.01).

Conclusions: The Doppler CO2 test seems to be a valuable method of estimating the risk of stroke in patients with carotid artery occlusions.

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