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. 2004 Dec 28;63(12):2381-3.
doi: 10.1212/01.wnl.0000147259.34163.33.

Antibodies against glycosylated native MOG are elevated in patients with multiple sclerosis

Susanne Gaertner  1 , Katrien L de Graaf, Bernhard Greve, Robert Weissert
Affiliations

Antibodies against glycosylated native MOG are elevated in patients with multiple sclerosis

Susanne Gaertner et al. Neurology. .

Abstract

Antibodies against native glycosylated myelin-oligodendrocyte-glycoprotein (MOG) were measured by ELISA in patients with multiple sclerosis (MS) and controls. Anti-MOG IgM antibodies were elevated during the first demyelinating event. Higher MOG-specific IgG antibodies were found in patients during relapses and in secondary chronic progressive MS compared to patients in remission and healthy controls. Antibodies against native MOG may be a potential biomarker for MS.

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