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Comparative Study
. 2004 Nov-Dec;28(6):419-25.

[A prospective comparative study to assess the impact of pharmaceutical intervention in the promotion of sequential therapy with flouroquinolones]

[Article in Spanish]
M Pinteño Blanco  1 , O Delgado Sánchez, A Escrivá Torralva, M Crespí Monjo, P Ventayol Bosch, F Puigventós Latorre, I Martínez López
Affiliations
  • PMID: 15628944
Comparative Study

[A prospective comparative study to assess the impact of pharmaceutical intervention in the promotion of sequential therapy with flouroquinolones]

[Article in Spanish]
M Pinteño Blanco et al. Farm Hosp. 2004 Nov-Dec.

Abstract

Objective: To assess the impact of pharmaceutical intervention on the use of sequential therapy (ST) with fluoroquinolones.

Methods: A prospective comparative study of pharmaceutical intervention in two stages: observational stage and intervention stage for ST promotion.

Results: In all, 250 patients receiving intravenous therapy with fluoroquinolones (113 with levofloxacin and 137 with ciprofloxacin) were studied, with 76 and 70 patients, respectively, being eligible for a pharmaceutical intervention program to promote ST. Pharmaceutical intervention showed a decreased duration of intravenous therapy and increased duration of oral therapy for both drugs, as well as decreased medication-related costs, all in a statistically significant manner.

Discussion: ST promotion provides an opportunity to expand the role of hospital pharmacists and to optimize fluoroquinolone-based therapy, which results in decreased intravenous treatments and provides a more cost-effective option.

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