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Comparative Study
. 2005 Jan;26(1):8-9.
doi: 10.1016/j.tips.2004.10.010.

The recently deorphanized GPR80 (GPR99) proposed to be the P2Y15 receptor is not a genuine P2Y receptor

Maria P Abbracchio, Geoffrey Burnstock, Jean-Marie Boeynaems, Eric A Barnard, José L Boyer, Charles Kennedy, Maria Teresa Miras-Portugal, Brian F King, Christian Gachet, Kenneth A Jacobson, Gary A Weisman
Comparative Study

The recently deorphanized GPR80 (GPR99) proposed to be the P2Y15 receptor is not a genuine P2Y receptor

Maria P Abbracchio et al. Trends Pharmacol Sci. 2005 Jan.
No abstract available

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References

    1. Abbracchio MP et al. (2003) Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family. Trends Pharmacol. Sci 24, 52–55 - PMC - PubMed
    1. Boeynaems J-M et al. (2003) P2Y receptors: new subtypes, new functions. Drug Dev. Res 59, 30–35
    1. Inbe H et al. (2004) Identification and characterization of a cell-surface receptor, P2Y15, for AMP and adenosine. J. Biol. Chem 279, 19790–19799 - PubMed
    1. Wittenberger T et al. (2002) GPR99, a new G protein-coupled receptor with homology to a new subgroup of nucleotide receptors. BMC Genomics 3, 17–23 - PMC - PubMed
    1. He W et al. (2004) Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors. Nature 429, 188–936 - PubMed

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