Azathioprine and 6 Mercaptopurine in postoperative maintenance of Crohn's disease remission: is no evidence of effect an evidence of no effect?

Comment

Houssam E Mardini. Gastroenterology. 2005 Jan.

. 2005 Jan;128(1):246-8; author reply 248-9.

doi: 10.1053/j.gastro.2004.11.035.

No abstract available

Comment on

Postoperative maintenance of Crohn's disease remission with 6-mercaptopurine, mesalamine, or placebo: a 2-year trial.
Hanauer SB, Korelitz BI, Rutgeerts P, Peppercorn MA, Thisted RA, Cohen RD, Present DH. Hanauer SB, et al. Gastroenterology. 2004 Sep;127(3):723-9. doi: 10.1053/j.gastro.2004.06.002. Gastroenterology. 2004. PMID: 15362027 Clinical Trial.
Azathioprine and mesalamine for prevention of relapse after conservative surgery for Crohn's disease.
Ardizzone S, Maconi G, Sampietro GM, Russo A, Radice E, Colombo E, Imbesi V, Molteni M, Danelli PG, Taschieri AM, Bianchi Porro G. Ardizzone S, et al. Gastroenterology. 2004 Sep;127(3):730-40. doi: 10.1053/j.gastro.2004.06.051. Gastroenterology. 2004. PMID: 15362028 Clinical Trial.
The efficacy of azathioprine and 6-mercaptopurine for the prevention of postoperative recurrence in patients with Crohn's disease remains uncertain.
Sandborn WJ, Feagan BG. Sandborn WJ, et al. Gastroenterology. 2004 Sep;127(3):990-3. doi: 10.1053/j.gastro.2004.07.037. Gastroenterology. 2004. PMID: 15362055 No abstract available.