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. 2005 Jan 5:5:2.
doi: 10.1186/1471-2458-5-2.

Patients' request for and emergency physicians' prescription of antimicrobial prophylaxis for anthrax during the 2001 bioterrorism-related outbreak

Nkuchia M M'ikanatha  1 , Kathleen G Julian, Allen R Kunselman, Robert C Aber, James T Rankin, Ebbing Lautenbach
Affiliations

Patients' request for and emergency physicians' prescription of antimicrobial prophylaxis for anthrax during the 2001 bioterrorism-related outbreak

Nkuchia M M'ikanatha et al. BMC Public Health. .

Abstract

Background: Inappropriate use of antibiotics by individuals worried about biological agent exposures during bioterrorism events is an important public health concern. However, little is documented about the extent to which individuals with self-identified risk of anthrax exposure approached physicians for antimicrobial prophylaxis during the 2001 bioterrorism attacks in the United States.

Methods: We conducted a telephone survey of randomly selected members of the Pennsylvania Chapter of the American College of Emergency Physicians to assess patients' request for and emergency physicians' prescription of antimicrobial agents during the 2001 anthrax attacks.

Results: Ninety-seven physicians completed the survey. Sixty-four (66%) respondents had received requests from patients for anthrax prophylaxis; 16 (25%) of these physicians prescribed antibiotics to a total of 23 patients. Ten physicians prescribed ciprofloxacin while 8 physicians prescribed doxycycline.

Conclusion: During the 2001 bioterrorist attacks, the majority of the emergency physicians we surveyed encountered patients who requested anthrax prophylaxis. Public fears may lead to a high demand for antibiotic prophylaxis during bioterrorism events. Elucidation of the relationship between public health response to outbreaks and outcomes would yield insights to ease burden on frontline clinicians and guide strategies to control inappropriate antibiotic allocation during bioterrorist events.

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Figures

Figure 1
Figure 1
Types of antibiotics prescribed by emergency physicians. A total of 16 physicians prescribed various antibiotics shown above. Fifteen physicians prescribed these types of drugs to 23 patients. One physician did not respond to the question on the number of patients the physician had given anthrax prophylaxis.
See this image and copyright information in PMC

References

    1. Silver RC, Holman EA, McIntosh DN, Poulin M, Gil-Rivas V. Nationwide longitudinal study of psychological responses to September 11. JAMA. 2002;288:1235–1244. doi: 10.1001/jama.288.10.1235. - DOI - PubMed
    1. Centers for Disease Control and Prevention Update: investigations of bioterrorism-related anthrax and interim guidelines for clinical evaluation of persons with possible anthrax. MMWR Morb Mortal Wkly Rep. 2001;50:941–948. - PubMed
    1. Centers for Disease Control and Prevention Anthrax: MMWR References http://www.bt.cdc.gov/agent/anthrax/reference/mmwr.asp.
    1. Inglesby TV, Henderson DA, Bartlett JG, et al. Anthrax as a biological weapon: medical and public health management. JAMA. 1999;281:1735–1745. doi: 10.1001/jama.281.18.1735. - DOI - PubMed
    1. Centers for Disease Control and Prevention Update: investigation of bioterrorism-related anthrax and interim guidelines for exposure management and antimicrobial therapy, October 2001. MMWR Morb Mortal Wkly Rep. 2001;50:909–919. - PubMed

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