Bacterial conjugation: a potential tool for genomic engineering
- PMID: 15636742
- DOI: 10.1016/j.resmic.2004.07.008
Bacterial conjugation: a potential tool for genomic engineering
Abstract
Bacterial conjugation is a mechanism for horizontal DNA transfer with potential for universal DNA delivery. The conjugal machinery can be separated into three functional modules: the relaxosome, the coupling protein, and a type IV protein secretion system. Module interchangeability among different conjugative systems opens up the possibility of "a la carte" engineering of DNA delivery into virtually any cell type.
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