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. 2005 Jan;23(1):137-44.
doi: 10.1038/nbt1053.

Assessing computational tools for the discovery of transcription factor binding sites

Martin Tompa  1 , Nan Li, Timothy L Bailey, George M Church, Bart De Moor, Eleazar Eskin, Alexander V Favorov, Martin C Frith, Yutao Fu, W James Kent, Vsevolod J Makeev, Andrei A Mironov, William Stafford Noble, Giulio Pavesi, Graziano Pesole, Mireille Régnier, Nicolas Simonis, Saurabh Sinha, Gert Thijs, Jacques van Helden, Mathias Vandenbogaert, Zhiping Weng, Christopher Workman, Chun Ye, Zhou Zhu
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Free article

Assessing computational tools for the discovery of transcription factor binding sites

Martin Tompa et al. Nat Biotechnol. 2005 Jan.
Free article

Abstract

The prediction of regulatory elements is a problem where computational methods offer great hope. Over the past few years, numerous tools have become available for this task. The purpose of the current assessment is twofold: to provide some guidance to users regarding the accuracy of currently available tools in various settings, and to provide a benchmark of data sets for assessing future tools.

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