doi: 10.1128/iai.60.5.2096-2100.1992.
Fate of conidia of Paracoccidioides brasiliensis after ingestion by resident macrophages or cytokine-treated macrophages
Affiliations
- PMID: 1563800
- PMCID: PMC257120
- DOI: 10.1128/iai.60.5.2096-2100.1992
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Fate of conidia of Paracoccidioides brasiliensis after ingestion by resident macrophages or cytokine-treated macrophages
Infect Immun.
1992 May.
Abstract
Conidia ingested by resident macrophages had an enhanced percentage of transformation to yeast cells compared with those in culture medium without macrophages. The yeast cells subsequently grew intracellularly by budding. Macrophages treated with cytokines from antigen-stimulated spleen cells from immunized mice significantly inhibited transformation of ingested conidia.
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