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. 1992 May;60(5):2096-100.
doi: 10.1128/iai.60.5.2096-2100.1992.

Fate of conidia of Paracoccidioides brasiliensis after ingestion by resident macrophages or cytokine-treated macrophages

L E Cano  1 , E Brummer, D A Stevens, A Restrepo
Affiliations

Fate of conidia of Paracoccidioides brasiliensis after ingestion by resident macrophages or cytokine-treated macrophages

L E Cano et al. Infect Immun. 1992 May.

Abstract

Conidia ingested by resident macrophages had an enhanced percentage of transformation to yeast cells compared with those in culture medium without macrophages. The yeast cells subsequently grew intracellularly by budding. Macrophages treated with cytokines from antigen-stimulated spleen cells from immunized mice significantly inhibited transformation of ingested conidia.

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