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Review
. 2005 Feb;31(1):1-17, vii.
doi: 10.1016/j.rdc.2004.10.003.

Developments in glucocorticoid therapy

Johannes W J Bijlsma  1 , Kenneth G Saag, Frank Buttgereit, José A P da Silva
Affiliations
Review

Developments in glucocorticoid therapy

Johannes W J Bijlsma et al. Rheum Dis Clin North Am. 2005 Feb.

Abstract

Recent evidence for a disease-modifying potential of low-dose glucocorticoids (GCs) in the treatment of rheumatoid arthritis has renewed the debate on the risk benefit ratio with this therapy. Two recent developments are described that might have a positive influence on these risk benefit ratios. One is the improvement in new GC compounds--designer GCs, alterations in bioactivity, and alterations in formulations. The other is a better understanding and management of the toxicity of GCs.

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