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Review
. 2005 Jan;71(1):20-8.
doi: 10.1128/AEM.71.1.20-28.2005.

Amoebae as training grounds for intracellular bacterial pathogens

Maëlle Molmeret  1 , Matthias Horn, Michael Wagner, Marina Santic, Yousef Abu Kwaik
Affiliations
Review

Amoebae as training grounds for intracellular bacterial pathogens

Maëlle Molmeret et al. Appl Environ Microbiol. 2005 Jan.
No abstract available

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Figures

FIG. 1.
FIG. 1.
16S rRNA-based phylogenetic tree showing the affiliation of L. pneumophila and obligate endosymbionts of free-living protozoa. Bar, 10% estimated evolutionary distance.
FIG. 2.
FIG. 2.
Electron micrograph of environmental chlamydiae within an Acanthamoeba host cell. The two different stages of the developmental cycle are indicated by black (reticulate bodies) and white (elementary bodies) arrows. N, nucleus; bar, 1 μm.
FIG. 3.
FIG. 3.
Electron micrographs of U937 macrophages (A) and A. polyphaga (B) infected by L. pneumophila (strain AA100) at 24 h. The infection is very similar in both host cells. Legionella is cytoplasmic at 24 h in the two panels.
FIG. 4.
FIG. 4.
Electron micrograph of U937 cells infected by L. pneumophila at 8 h postinfection. The LCP is intact and is surrounded by the endoplasmic reticulum.
See this image and copyright information in PMC

References

    1. Abd, H., T. Johansson, I. Golovliov, G. Sandström, and M. Forsman. 2003. Survival and growth of Francisella tularensis in Acanthamoeba castellanii. Appl. Environ. Microbiol. 69:600-606. - PMC - PubMed
    1. Abu Kwaik, Y. 1998. Induced expression of the Legionella pneumophila gene encoding a 20-kilodalton protein during intracellular infection. Infect. Immun. 66:203-212. - PMC - PubMed
    1. Abu Kwaik, Y. 1996. The phagosome containing Legionella pneumophila within the protozoan Hartmanella vermiformis is surrounded by the rough endoplasmic reticulum. Appl. Environ. Microbiol. 62:2022-2028. - PMC - PubMed
    1. Abu Kwaik, Y., L.-Y. Gao, O. S. Harb, and B. J. Stone. 1997. Transcriptional regulation of the macrophage-induced gene (gspA) of Legionella pneumophila and phenotypic characterization of a null mutant. Mol. Microbiol. 24:629-642. - PubMed
    1. Abu Kwaik, Y., L.-Y. Gao, B. J. Stone, C. Venkataraman, and O. S. Harb. 1998. Invasion of protozoa by Legionella pneumophila and its role in bacterial ecology and pathogenesis. Appl. Environ. Microbiol. 64:3127-3133. - PMC - PubMed

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