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. 2005 Feb;38(2):180-2.
doi: 10.1016/j.clinbiochem.2004.10.015.

Circulating pregnancy-associated plasma protein A is not an early marker of acute myocardial infarction

Alberto Dominguez-Rodriguez  1 , Pedro Abreu-Gonzalez, Martín Garcia-Gonzalez, Julio Ferrer, Manuel Vargas
Affiliations

Circulating pregnancy-associated plasma protein A is not an early marker of acute myocardial infarction

Alberto Dominguez-Rodriguez et al. Clin Biochem. 2005 Feb.

Abstract

Objective: The purpose of this study was to assess whether serum levels of pregnancy-associated plasma protein A (PAPP-A) are elevated early in patients with acute myocardial infarction (AMI).

Design and methods: We measured serum levels of PAPP-A in 80 patients with AMI and in 80 age-matched healthy control subjects. The mean (+/-SEM) time from onset of symptoms to blood sampling was 6.3 +/- 2.8 h in the group with AMI.

Results: The PAPP-A levels did not differ between the control group and the AMI group (1.24 +/- 0.07 vs. 1.29 +/- 0.02 mIU/l; P = 0.54).

Conclusions: Measurement of serum PAPP-A does not seem to be a useful early marker for AMI.

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