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. 2005 Jan 15;95(2):277-80.
doi: 10.1016/j.amjcard.2004.09.018.

Refeeding normalizes the QT rate dependence of female anorexic patients

Frédéric Roche  1 , Jean-Claude Barthélémy, Norbert Mayaud, Vincent Pichot, David Duverney, Natacha Germain, François Lang, Bruno Estour
Affiliations

Refeeding normalizes the QT rate dependence of female anorexic patients

Frédéric Roche et al. Am J Cardiol. .

Abstract

We postulated that dynamic alterations in QT interval adaptation could characterize patients with anorexia nervosa (AN) and could be restored after weight gain. To assess ventricular repolarization features, we evaluated the QT dynamicity along RR intervals from 24-hour electrocardiographic data of patients with AN before and after refeeding. Ten young women with AN (19 +/- 3 years) were included in the study. The QT/RR slope was found significantly enhanced compared with normals (-1.82 +/- 0.62 vs -1.40 +/- 0.30; p < 0.05). This slope returned to normal range values after refeeding. The QT/RR slope was significantly correlated with the body mass index (r = 0.59; p < 0.007) in the patient group.

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Comment in

  • QT dispersion in anorexia nervosa.
    Mehler PS, Krantz MJ. Mehler PS, et al. Am J Cardiol. 2005 Oct 1;96(7):1034. doi: 10.1016/j.amjcard.2005.03.025. Am J Cardiol. 2005. PMID: 16188538 No abstract available.

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