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Review
. 2005 Jan;146(1):134-6.
doi: 10.1016/j.jpeds.2004.09.014.

Pediatric hypereosinophilic syndrome (HES) differs from adult HES

Hary T Katz  1 , S Jaharul Haque, Fred H Hsieh
Affiliations
Review

Pediatric hypereosinophilic syndrome (HES) differs from adult HES

Hary T Katz et al. J Pediatr. 2005 Jan.

Abstract

The idiopathic hypereosinophilic syndrome (HES) developed in a 15-year-old boy who presented with colitis, cough, rash, and hepatitis. Molecular analysis failed to demonstrate the Fip1-like1-Platelet Derived Growth Factor Receptor alpha chain (FIP1L1-PDGFRA) mutation described in adult patients with HES. There are significant clinical differences between the pediatric and adult presentations of HES.

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