Toll-like receptor 4 gene in IBD: further evidence for genetic heterogeneity in Europe
- PMID: 15647200
- PMCID: PMC1774822
Toll-like receptor 4 gene in IBD: further evidence for genetic heterogeneity in Europe
Comment on
-
Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis.Gut. 2004 Jul;53(7):987-92. doi: 10.1136/gut.2003.030205. Gut. 2004. PMID: 15194649 Free PMC article.
References
-
- Arbour NC, Lorenz E. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet 2000;25:187–91. - PubMed
-
- Torok HP, Glas J, Tonenchi L, et al. Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis. Clin Immunol 2004;112:85–91. - PubMed
-
- Arnott ID, Nimmo ER. NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn’s disease patients: evidence for genetic heterogeneity within Europe? Genes Immun 2004;5:417–25. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources