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Comment
. 2005 Jan 11;15(1):R14-6.
doi: 10.1016/j.cub.2004.12.011.

Notochord morphogenesis: a prickly subject for ascidians

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Notochord morphogenesis: a prickly subject for ascidians

Masazumi Tada. Curr Biol. .
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Abstract

Orchestrated cell movements marshalled by proper cell polarity in the developing body axes are fundamental to the elongation of the notochord during chordate embryogenesis. A recent study shows that, in ascidians, the planar cell polarity gene prickle regulates sequential establishment of cell polarity during two phases of notochord morphogenesis.

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