Notochord morphogenesis: a prickly subject for ascidians
- PMID: 15649343
- DOI: 10.1016/j.cub.2004.12.011
Notochord morphogenesis: a prickly subject for ascidians
Abstract
Orchestrated cell movements marshalled by proper cell polarity in the developing body axes are fundamental to the elongation of the notochord during chordate embryogenesis. A recent study shows that, in ascidians, the planar cell polarity gene prickle regulates sequential establishment of cell polarity during two phases of notochord morphogenesis.
Comment on
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Ascidian prickle regulates both mediolateral and anterior-posterior cell polarity of notochord cells.Curr Biol. 2005 Jan 11;15(1):79-85. doi: 10.1016/j.cub.2004.12.041. Curr Biol. 2005. PMID: 15700379
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