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Review
. 2005 Feb:20:36-42.
doi: 10.1152/physiol.00033.2004.

Endothelial progenitor cells for vasculogenesis

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Free article
Review

Endothelial progenitor cells for vasculogenesis

Satoshi Murasawa et al. Physiology (Bethesda). 2005 Feb.
Free article

Abstract

Postnatal vasculogenesis is considered to be involved in neovascularization of adult tissues, because bone marrow-derived endothelial progenitor cells (EPCs) were isolated from circulating mononuclear cells in peripheral blood and were shown to incorporate into sites of physiological and pathological neovascularization and to differentiate into mature endothelial cells. EPCs might have an attractive potential therapeutic application for cardiovascular ischemic diseases as a novel cell-based strategy mainly via a vasculogenesis mechanism.

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