Review
doi: 10.1089/apc.2004.18.687.
Rhabdomyolysis after simvastatin therapy in an HIV-infected patient with chronic renal failure
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- PMID: 15659879
- DOI: 10.1089/apc.2004.18.687
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Review
Rhabdomyolysis after simvastatin therapy in an HIV-infected patient with chronic renal failure
AIDS Patient Care STDS.
2004 Dec.
Abstract
We encountered a 49-year-old HIV-infected man with chronic renal insufficiency who developed rhabdomyolysis after treatment with simvastatin. He recovered after initiating hemodialysis and discontinuing oral medications. Rhabdomyolysis most likely resulted from an excessive blood concentration of simvastatin caused by concomitant use of fluconazole in the presence of renal insufficiency.
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