Antiphospholipid antibody syndrome (APS) presenting as splenic thrombosis and acute acalculous cholecystitis

Abstract

Antiphospholipid syndrome is an uncommon auto-immune disease presenting with various clinical manifestations that may lead to surgical intervention and sometimes even life-threatening emergencies. This syndrome presents with venous and arterial thrombosis of many organs such as liver, kidney and of the skin etc. Clinical manifestations may mimic hematological disorders and be misdiagnosed in some cases due to the complexity of the symptoms. In the present study, a 65-year-old man with APS syndrome presenting with severe abdominal organ pathologies that required surgical intervention, is reported.