Review
doi: 10.1007/s11892-005-0069-1.
Diabetes and brain aging: epidemiologic evidence
Affiliations
- PMID: 15663919
- DOI: 10.1007/s11892-005-0069-1
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Review
Diabetes and brain aging: epidemiologic evidence
Curr Diab Rep.
2005 Feb.
Abstract
Increasingly, data from epidemiologic studies suggest diabetes is a risk factor in old age for brain aging, including cognitive impairment and dementia. These associations may reflect a direct effect on the brain of hyperglycemia, or the effects of the diabetes-associated comorbidities of hypertension, dyslipidemia, or hyperinsulinemia. Epidemiologic data on diabetes and brain aging are reviewed. A brief overview is also given of the physiologic mechanisms supporting the epidemiologic data.
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