Raf phosphorylation: one step forward and two steps back
- PMID: 15664184
- DOI: 10.1016/j.molcel.2005.01.001
Raf phosphorylation: one step forward and two steps back
Abstract
We understand Raf-1 activation relatively well but know less about how it is inactivated. An exciting study in this issue of Molecular Cell now describes the molecular basis underlying the transient nature of Raf-1 signaling.
Comment on
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Regulation of Raf-1 by direct feedback phosphorylation.Mol Cell. 2005 Jan 21;17(2):215-24. doi: 10.1016/j.molcel.2004.11.055. Mol Cell. 2005. PMID: 15664191
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