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Comment
. 2005 Jan 21;17(2):166-7.
doi: 10.1016/j.molcel.2005.01.002.

Domain swapping and retroviral assembly

Richard L Kingston  1 , Volker M Vogt
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Free article
Comment

Domain swapping and retroviral assembly

Richard L Kingston et al. Mol Cell. .
Free article

Abstract

The structure of a mammalian SCAN domain has been recently reported. The molecule is a structural homolog of the HIV-1 capsid protein and forms a domain-swapped dimer in solution. The authors propose a similar domain-swapping event facilitates HIV-1 assembly, providing a new model for protein-protein interactions underlying viral particle formation.

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