Free radical lipid oxidation in brain cortex neurons and neuroglia during convulsions
- PMID: 15665939
- DOI: 10.1007/s10517-005-0036-5
Free radical lipid oxidation in brain cortex neurons and neuroglia during convulsions
Abstract
The amount of lipid peroxidation products (conjugated dienes and trienes and Schiff bases) in cortical neurons of the cerebral hemispheres decreased by 30% at the peak of convulsions observed 10-15 min after intraperitoneal injection of picrotoxin. In neuroglial cells of control animals the intensity of lipid peroxidation in was 1.7-2.0 times lower. Picrotoxin had no effect on this parameter.
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