Review
doi: 10.1111/j.1399-3046.2004.00231.x.
Basic mechanisms of humoral rejection
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- PMID: 15667605
- DOI: 10.1111/j.1399-3046.2004.00231.x
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Review
Basic mechanisms of humoral rejection
Pediatr Transplant.
2005 Feb.
Abstract
Humoral rejection is among the most vexing problems afflicting organ transplants. Triggered by antibodies predominantly against donor human leukocyte (HLA), humoral rejection can now be understood through consideration of basic mechanisms of immunity to foreign antigens and impact of humoral immunity on blood vessels. Basic considerations may also shed light on mechanisms by which various treatments have recently brought about vastly improved outcomes.
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