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. 2005 Jan 26;15(2):R61-4.
doi: 10.1016/j.cub.2004.12.057.

MicroRNA biogenesis: drosha can't cut it without a partner

Yukihide Tomari  1 , Phillip D Zamore
Affiliations
Free article

MicroRNA biogenesis: drosha can't cut it without a partner

Yukihide Tomari et al. Curr Biol. .
Free article

Abstract

The ribonuclease Drosha requires a dedicated double-stranded RNA binding protein to convert long, nuclear primary microRNA transcripts into shorter pre-microRNA stem-loops, the cytoplasmic precursors from which mature microRNAs are ultimately excised.

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