beta-Catenin: a pivot between cell adhesion and Wnt signalling
- PMID: 15668160
- DOI: 10.1016/j.cub.2004.12.058
beta-Catenin: a pivot between cell adhesion and Wnt signalling
Abstract
Mutual adhesion of animal cells is intimately linked to Wnt signaling through a shared component: beta-catenin, or Armadillo in Drosophila. Recent work indicates how beta-catenin shifts from cell adhesion to Wnt signaling, a switch associated with epithelial-mesenchymal transitions and cancer.
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