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Review
. 2005 Jan-Feb;25(1):13-22.
doi: 10.1159/000083477. Epub 2005 Jan 20.

Cellular oxidative processes in relation to renal disease

E Nigel Wardle  1
Affiliations
Review

Cellular oxidative processes in relation to renal disease

E Nigel Wardle. Am J Nephrol. 2005 Jan-Feb.

Abstract

This article summarizes the biochemical processes that produce reactive oxygen species (ROS) and other mediators that account for 'oxidative stress'. Formation of ROS in signal transduction cascades is illustrated from studies of kidney cell systems. The pathophysiological implications for the nephrologist are then reviewed.

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