Two decades of advances in understanding of mild traumatic brain injury
- PMID: 15668567
- DOI: 10.1097/00001199-200501000-00003
Two decades of advances in understanding of mild traumatic brain injury
Abstract
The aim of this article is to highlight advances achieved over the past 2 decades in understanding mild traumatic brain injury (MTBI). The first section provides a historical background, which establishes that research during the 1980s was focused on more severe TBI. During the 1990s MTBI received substantially more recognition. The second section explains why the diagnostic frameworks have evolved. The third section examines why 80% to 90% of all MTBI patients have favorable outcomes whereas 10% to 20% do not. This latter subgroup, also known as the Miserable Minority, presents with a plethora of persistent physical, emotional, and cognitive symptoms. A dichotomy has emerged in the literature interpreting these postconcussional symptoms as being psychogenic or neurogenic. This article offers an alternate and more patient-based framework. Instead of the various disciplines focusing on select symptoms, the patient-based approach is aimed at phenomenologically understanding how the MTBI patient's life has changed. The fourth section provides practical steps for treatments. This historical review offers the conclusion that we have focused for too long on diagnostic challenges, without similarly focusing on treatment. It is time that we advance efficacious treatments for the Miserable Minority.
Similar articles
-
Methodological issues and research recommendations for prognosis after mild traumatic brain injury: results of the International Collaboration on Mild Traumatic Brain Injury Prognosis.Arch Phys Med Rehabil. 2014 Mar;95(3 Suppl):S265-77. doi: 10.1016/j.apmr.2013.04.026. Arch Phys Med Rehabil. 2014. PMID: 24581912
-
Detection of neurofilament-H in serum as a diagnostic tool to predict injury severity in patients who have suffered mild traumatic brain injury.J Neurosurg. 2014 Nov;121(5):1232-8. doi: 10.3171/2014.7.JNS132474. Epub 2014 Sep 5. J Neurosurg. 2014. PMID: 25192482
-
Diffusion tensor imaging in mild traumatic brain injury litigation.J Am Acad Psychiatry Law. 2011;39(4):511-23. J Am Acad Psychiatry Law. 2011. PMID: 22159979 Review.
-
Symptoms associated with mild traumatic brain injury/concussion: the role of bother.J Neurosci Nurs. 2013 Jun;45(3):124-32. doi: 10.1097/JNN.0b013e31828a418b. J Neurosci Nurs. 2013. PMID: 23558978
-
Spectrum of traumatic brain injury from mild to severe.Surg Clin North Am. 2012 Aug;92(4):939-57, ix. doi: 10.1016/j.suc.2012.04.005. Epub 2012 Jun 5. Surg Clin North Am. 2012. PMID: 22850156 Review.
Cited by
-
Bidirectional Changes in Anisotropy Are Associated with Outcomes in Mild Traumatic Brain Injury.AJNR Am J Neuroradiol. 2016 Nov;37(11):1983-1991. doi: 10.3174/ajnr.A4851. Epub 2016 Jun 9. AJNR Am J Neuroradiol. 2016. PMID: 27282864 Free PMC article.
-
Medical care costs associated with traumatic brain injury over the full spectrum of disease: a controlled population-based study.J Neurotrauma. 2012 Jul 20;29(11):2038-49. doi: 10.1089/neu.2010.1713. Epub 2012 Apr 26. J Neurotrauma. 2012. PMID: 22414023 Free PMC article.
-
Blue-Light Therapy following Mild Traumatic Brain Injury: Effects on White Matter Water Diffusion in the Brain.Front Neurol. 2017 Nov 22;8:616. doi: 10.3389/fneur.2017.00616. eCollection 2017. Front Neurol. 2017. PMID: 29213254 Free PMC article.
-
Functional Magnetic Resonance Imaging of Cognitive Control following Traumatic Brain Injury.Front Neurol. 2017 Aug 4;8:352. doi: 10.3389/fneur.2017.00352. eCollection 2017. Front Neurol. 2017. PMID: 28824524 Free PMC article. Review.
-
Multi-Modal Analysis of Resting-State fMRI Data in mTBI Patients and Association With Neuropsychological Outcomes.Front Neurol. 2021 May 17;12:639760. doi: 10.3389/fneur.2021.639760. eCollection 2021. Front Neurol. 2021. PMID: 34079510 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Miscellaneous