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. 2005 Feb;31(1):16-21.
doi: 10.1111/j.1447-0756.2005.00246.x.

Cervical Ureaplasma urealyticum colonization might be associated with increased incidence of preterm delivery in pregnant women without prophlogistic microorganisms on routine examination

Masahiro Mitsunari  1 , Souichi Yoshida, Imari Deura, Sayako Horie, Satoru Tsukihara, Tasuku Harada, Takashi Irie, Naoki Terakawa
Affiliations

Cervical Ureaplasma urealyticum colonization might be associated with increased incidence of preterm delivery in pregnant women without prophlogistic microorganisms on routine examination

Masahiro Mitsunari et al. J Obstet Gynaecol Res. 2005 Feb.

Abstract

Aim: We examined whether the detection of Ureaplasma urealyticum DNA in the cervix is associated with preterm labor and delivery.

Methods: Eighty-two women (23 preterm labor cases and 59 controls) with no evidence of prophlogistic microorganisms on routine microbiologic examination were enrolled for this study. U. urealyticum colonization was examined using polymerase chain reaction of cervical swabs.

Results: The positivity rate of U. urealyticum DNA in preterm labor cases was significantly higher than that in the controls (87.0%vs 45.8%, P=0.0007). Women in the U. urealyticum-positive group more frequently delivered preterm compared with those in the negative group (36.2%vs 11.4%, P=0.0111). In five cases that delivered preterm with histologically confirmed chorioamnionitis, U. urealyticum DNA was detected in the placenta.

Conclusions: Cervical U. urealyticum colonization might be associated with preterm labor and delivery.

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