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Randomized Controlled Trial
. 2005 Jan-Feb;3(1):7-14.
doi: 10.1370/afm.256.

Cost-effectiveness of enhancing primary care depression management on an ongoing basis

Kathryn Rost  1 , Jeffrey M Pyne, L Miriam Dickinson, Anthony T LoSasso
Affiliations
Randomized Controlled Trial

Cost-effectiveness of enhancing primary care depression management on an ongoing basis

Kathryn Rost et al. Ann Fam Med. 2005 Jan-Feb.

Abstract

Purpose: Although potentially costly, enhancing primary care depression management on an ongoing basis results in substantial long-term treatment effectiveness. The purpose of this article is to compare the cost-effectiveness of this approach with that of usual care.

Methods: The study was conducted in 12 community primary care practices randomized to enhanced or usual care after stratification by baseline practice patterns. Practices assigned to enhanced care encouraged depressed patients to engage in active treatment, using practice nurses to provide regularly scheduled care management during the course of 24 months. We analyze outcomes for 211 adults (73.4% of potential eligible patients) beginning a new treatment episode for major depression determined by previsit screening. Outcomes included blinded estimates of days free of depression impairment as well as health care costs for 2 years.

Results: Enhanced care significantly increased the number of days free of depression impairment for 2 years when compared with usual care (647.6 days vs 588.2 days, P <.01). The incremental cost-effectiveness ratio for enhanced care ranged from 9,592 dollars to 14,306 dollars per quality-adjusted life-year (QALY). The number of incremental days free of depression impairment increased between the first year and the second year (23.0 vs 36.4, respectively, P <.001) while incremental health plan costs decreased significantly (568 dollars vs -12 dollars, P <.001).

Conclusions: Enhancing primary care depression management on an ongoing basis should be considered for adoption by policy and health plan leaders.

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Figures

Figure 1.
Figure 1.
Patient recruitment and participation flowchart. * A total of 110 patients received any program contact, including 2 patients who participated after 6 months only.
Figure 2.
Figure 2.
Enhanced care effect on outcomes (n=211).
See this image and copyright information in PMC

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References

    1. Murray C, Lopez A, eds. The Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability from Diseases, Injuries, and Risk Factors in 1990 and Projected to 2020. Boston: The Harvard School of Public Health on Behalf of the World Health Organization and the World Bank; 1996.
    1. Katon W, Von Korff M, Lin E, et al. Collaborative management to achieve treatment guidelines: impact on depression in primary care. JAMA. 1995;273:1026–1031. - PubMed
    1. Mynors-Wallis LM, Gath DH, Day A, Baker F. Randomised controlled trial of problem solving treatment, antidepressant medication, and combined treatment for major depression in primary care. BMJ. 2000;320:26–30. - PMC - PubMed
    1. Katon W, Robinson P, Von Korff M, et al. A multifaceted intervention to improve treatment of depression in primary care. Arch Gen Psychiatry. 1996;53:924–932. - PubMed
    1. Schulberg HC, Block MR, Madonia MJ, et al. Treating major depression in primary care practice: eight-month clinical outcomes. Arch Gen Psychiatry. 1996;53:913–919. - PubMed

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