Interaction of retention interval with CS-preexposure and extinction treatments: symmetry with respect to primacy

Abstract

Imposition of a retention interval between cue-outcome pairings and testing can alleviate the retardation of conditioned responding induced by pretraining exposure to the cue (i.e., the CS-preexposure effect). However, recent studies have reported an enhanced effect of CS-preexposure treatment with longer retention intervals (De la Casa & Lubow, 2000, 2002; Lubow & De la Casa, 2002). In a series of conditioned barpress suppression studies with rats, we examined the effects of imposing a retention interval just prior to testing following either CS-preexposure (cue alone before cue-outcome pairings) or extinction (cue alone after cue-outcome pairings) treatments. Experiment 1 replicated in a different preparation recent reports of CS-preexposure treatment effects increasing with longer retention intervals. Experiment 2 showed that spontaneous recovery of stimulus control of behavior after extinction can be obtained with the same parameters as those used to observe the augmented effect of CS-preexposure treatment. In Experiment 3, both the augmented effect of CS-preexposure treatment and spontaneous recovery from extinction were found when we used, in place of a retention interval, an associative priming manipulation.