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Review
. 2004 Oct;4(2):78-85.
doi: 10.1007/s10238-004-0041-4.

Timely reconstitution of immune competence affects clinical outcome following autologous stem cell transplantation

L F Porrata  1 , S N Markovic
Affiliations
Review

Timely reconstitution of immune competence affects clinical outcome following autologous stem cell transplantation

L F Porrata et al. Clin Exp Med. 2004 Oct.

Abstract

The anti-tumor activity of the immune system in the setting of hematopoietic stem cell transplantation has largely been described in the context of the "graft-versus-tumor" effect of allogeneic stem cell transplantation. This article reviews clinical evidence suggesting the existence of an autologous graft-versus-tumor effect in the setting of host immune system recovery following autologous stem cell transplantation resulting in prolongation of survival of cancer patients.

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