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. 2004;31(4):269-70.

Cytokines and endometriosis

J Markowska  1 , M Kowalska, M Gogacz, J Lubin, M Markowski, J Kamińska
Affiliations
  • PMID: 15672963

Cytokines and endometriosis

J Markowska et al. Clin Exp Obstet Gynecol. 2004.

Abstract

Introduction: Abnormal expression of cytokines is considered to be involved in the pathogenesis of endometriosis.

Material and methods: In 63 women with various stages of endometriosis preoperative levels of cytokines, including IL-6, IL-8, BVEGF, b-FGF, of TNF RI and TNF RII were analysed employing ELISA tests (R&D kits).

Results: In the sera of endometriosis patients significantly augmented levels of IL-6 and of b-FGF were detected as well as a trend for elevated IL-8 levels.

Conclusion: Elevated serum levels of cytokines may show poor correspondence to the localized pathological process. Endometriosis would find a stricter reflection in cytokine levels in fluids or tissues of the pelvis minor.

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