Radiation risk is linear with dose at low doses
- PMID: 15673520
- DOI: 10.1259/bjr/51173413
Radiation risk is linear with dose at low doses
Abstract
This paper presents a brief argument, based on a mechanistic approach, to show that radiation risk is linear with radiation dose from zero dose up. Similarities in cellular effects lead to the assumption of a common mechanism and the DNA double strand break is identified as the crucial radiation-induced lesion. A cancer model extends the cellular effects to the main radiation risk providing confirmation of the dose effect for cancer at low doses.
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