Antistaphylococcal activity of dalbavancin, an experimental glycopeptide
- PMID: 15673763
- PMCID: PMC547276
- DOI: 10.1128/AAC.49.2.770-772.2005
Antistaphylococcal activity of dalbavancin, an experimental glycopeptide
Abstract
Dalbavancin, tested against 146 staphylococci, was more potent than other drugs tested, with an MIC at which 50% of staphylococci were inhibited of 0.03 microg/ml and an MIC at which 90% of staphylococci were inhibited of 0.06 microg/ml by microdilution. For all strains, MICs of vancomycin, linezolid, ranbezolid, oritavancin, daptomycin, and quinupristin-dalfopristin were </=4.0 microg/ml. Dalbavancin was bactericidal at four times the MIC against all six strains tested.
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