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. 1992 Mar 31;183(3):1103-8.
doi: 10.1016/s0006-291x(05)80304-3.

A cold-regulated Arabidopsis gene encodes a polypeptide having potent cryoprotective activity

C Lin  1 , M F Thomashow
Affiliations

A cold-regulated Arabidopsis gene encodes a polypeptide having potent cryoprotective activity

C Lin et al. Biochem Biophys Res Commun. .

Abstract

We previously showed that cor15, a cold-regulated gene from Arabidopsis thaliana, encodes a 15 kDa polypeptide designated COR15. Here we report that COR15 has potent cryoprotective activity in an in vitro cryoprotection assay. Specifically, COR15 was very effective in protecting the cold-labile enzyme lactate dehydrogenase against freeze-inactivation; on a concentration basis, it was about 10(6) times more effective than sucrose and 10(2)-10(3) times more effective than other proteins including bovine serum albumin. The possible role of cor15 in cold acclimation is discussed.

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