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Case Reports
. 1992 Apr;35(4):443-8.
doi: 10.1002/art.1780350414.

Molecular diagnosis of Ureaplasma urealyticum septic arthritis in a patient with hypogammaglobulinemia

A H Lee  1 , T Ramanujam, P Ware, P H Edelstein, J J Brooks, B Freundlich, H R Schumacher Jr, R B Zurier, D B Weiner, W V Williams
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Case Reports

Molecular diagnosis of Ureaplasma urealyticum septic arthritis in a patient with hypogammaglobulinemia

A H Lee et al. Arthritis Rheum. 1992 Apr.

Abstract

Objective: We report a hypogammaglobulinemic patient with a destructive oligoarticular arthritis, whose synovial fluid cultures were repeatedly sterile.

Methods and results: We identified a Ureaplasma urealyticum infection in his affected joints, using a polymerase chain reaction (PCR) assay.

Conclusion: The PCR technique promises to be extremely valuable in the rapid and specific diagnosis of infectious arthritis.

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