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Review
. 2005 Feb;58(2):134-40.
doi: 10.1136/jcp.2004.019588.

ACP Best Practice No 181: Chemical pathology clinical investigation and management of nephrolithiasis

T M Reynolds  1
Affiliations
Review

ACP Best Practice No 181: Chemical pathology clinical investigation and management of nephrolithiasis

T M Reynolds. J Clin Pathol. 2005 Feb.

Abstract

Renal stones have afflicted humans for millennia but there is still no solution to this problem. This review discusses the laboratory and metabolic aspects of the clinical management of patients with renal stones, both primary and secondary in origin. First, non-pharmacological interventions such as increased fluid intake, decreased protein consumption, dietary changes in sodium, calcium, oxalate, potassium, purine, vitamins, and essential fatty acids are considered. Then specific pharmacological treatment to modify urine calcium, oxalate, urate, citrate, and acidity are considered. Finally, more unusual types of stone are examined.

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