doi: 10.1039/b415297b.
Epub 2005 Jan 6.
Synthesis of sedamine by tethered cyclofunctionalisation
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- PMID: 15678192
- DOI: 10.1039/b415297b
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Synthesis of sedamine by tethered cyclofunctionalisation
Org Biomol Chem.
.
Abstract
The piperidine alkaloid, (+)-sedamine has been synthesised starting from (S)-1-phenyl-3-butenol using a stereoselective, intramolecular palladium-catalysed cyclocarbonylation reaction of a substituted hydroxylamine.
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