[Paget's disease]

Abstract

The authors have observed several cases of Paget's disease in their Centre for the Study, Diagnosis and Therapy of Osteoporosis. They define this disease and describe the probable etiology by Paramyxoviruses, the macro- and microscopic anatomopathological changes, the clinical manifestations, the complications (that are sometimes deadly: sarcoma), the diagnostic resources and, finally, the latest therapeutic possibilities (combined calcitonin and diphosphonate) that are useful only in patients with pain or complications.