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. 2005 Feb;30(2):73-80.
doi: 10.1016/j.tibs.2004.12.005.

Are proteins made from a limited parts list?

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Are proteins made from a limited parts list?

Nicholas C Fitzkee et al. Trends Biochem Sci. 2005 Feb.

Abstract

Understanding the process of protein folding has been recognized as an important challenge for >70 years. It is, quintessentially, a thermodynamic problem and, arguably, thermodynamics is our most powerful discipline for understanding biological systems. Yet, despite all this, we still lack predictive understanding of protein folding. Is something missing from this picture?

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