Mathematical modeling of planar polarity
- PMID: 15691754
- DOI: 10.1016/j.devcel.2005.01.007
Mathematical modeling of planar polarity
Abstract
Although it is well established that the Frizzled receptor is involved in the transmission of polarity information from cell to cell in the Drosophila cuticle, its precise role is still unclear. A recent paper by presents a mathematical model of a feedback loop-based mechanism for propagation of polarity between cells that can account for the known functions of Frizzled.
Comment on
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Mathematical modeling of planar cell polarity to understand domineering nonautonomy.Science. 2005 Jan 21;307(5708):423-6. doi: 10.1126/science.1105471. Science. 2005. PMID: 15662015
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