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Comment
. 2005 Feb;8(2):140-1.
doi: 10.1016/j.devcel.2005.01.004.

Costal-2: a scaffold for kinases mediates Hedgehog signaling

Shunsuke Ishii  1
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Costal-2: a scaffold for kinases mediates Hedgehog signaling

Shunsuke Ishii. Dev Cell. 2005 Feb.
Free article

Abstract

Drosophila genetics has identified several components of the Hedgehog signaling pathway, but the mechanism by which they act remains elusive. In this issue of Developmental Cell, a report by Zhang et al. provides evidence that the kinesin-related protein Costal-2 forms a multi-component scaffold that mediates Hedgehog signaling.

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