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Case Reports
. 2005 Mar;36(3):e20-2.
doi: 10.1161/01.STR.0000155733.65215.c2. Epub 2005 Feb 3.

Localized reversible reduction of apparent diffusion coefficient in transient hypoglycemia-induced hemiparesis

J Böttcher  1 , A Kunze, C Kurrat, P Schmidt, G Hagemann, O W Witte, W A Kaiser
Affiliations
Case Reports

Localized reversible reduction of apparent diffusion coefficient in transient hypoglycemia-induced hemiparesis

J Böttcher et al. Stroke. 2005 Mar.

Abstract

Background and purpose: The pathophysiology of hypoglycemia shares a common mechanism with cerebral ischemia, but so far, little is known regarding MRI of humans with hypoglycemia.

Methods: We report a patient with left hemiparesis and dysarthria associated with a blood glucose level of 1.7 mmol/L. The patient recovered completely after glucose infusion.

Results: The initial diffusion-weighted imaging (DWI) showed increased signal intensities and a reduction of apparent diffusion coefficient (ADC) values localized in the corpus callosum (splenium) and asymmetrically in the corona radiata. After 48 hours, follow-up revealed complete recovery of DWI and ADC signal abnormalities.

Conclusions: To our knowledge, this is the first presentation of a case with transient hypoglycemia-induced focal neurological deficits revealing completely reversible MRI changes in terms of disturbed DWI and ADC with a peculiar as yet undescribed topography.

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