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Comparative Study
. 2004;7(4):202-10.
doi: 10.1159/000082263.

Personal characteristics of older primary care patients who provide a buccal swab for apolipoprotein E testing and banking of genetic material: the spectrum study

Hillary R Bogner  1 , Marsha N Wittink, Jon F Merz, Joseph B Straton, Peter F Cronholm, Peter V Rabins, Joseph J Gallo
Affiliations
Comparative Study

Personal characteristics of older primary care patients who provide a buccal swab for apolipoprotein E testing and banking of genetic material: the spectrum study

Hillary R Bogner et al. Community Genet. 2004.

Abstract

Objective: To determine the personal characteristics and reasons associated with providing a buccal swab for apolipoprotein E (APOE) genetic testing in a primary care study.

Methods: The study sample consisted of 342 adults aged 65 years and older recruited from primary care settings.

Results: In all, 88% of patients agreed to provide a DNA sample for APOE genotyping and 78% of persons providing a sample agreed to banking of the DNA. Persons aged 80 years and older and African-Americans were less likely to participate in APOE genotyping. Concern about confidentiality was the most common reason for not wanting to provide a DNA sample or to have DNA banked.

Conclusion: We found stronger relationships between sociodemographic variables of age and ethnicity with participation in genetic testing than we did between level of educational attainment, gender, function, cognition, and affect.

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