Hepatoprotective activity of Abutilon indicum on experimental liver damage in rats
- PMID: 15693709
- DOI: 10.1016/j.phymed.2003.09.009
Hepatoprotective activity of Abutilon indicum on experimental liver damage in rats
Abstract
The aqueous extract of Abutilon indicum was tested for hepatoprotective activity against carbon tetrachloride- and paracetamol-induced hepatotoxicities in rats. A. indicum exhibited significant hepatoprotective activity by reducing carbon tetrachloride- and paracetamol-induced change in bio-chemical parameters that was evident by enzymatic examination. The plant extract may interfere with free-radical formation, which may conclude in hepatoprotective action. Acute toxicity studies revealed that the LD50 value is more than the dose of 4 g/kg body wt.