Bile acid and sterol solubilization in 2-hydroxypropyl-beta-cyclodextrin
- PMID: 1569391
Bile acid and sterol solubilization in 2-hydroxypropyl-beta-cyclodextrin
Abstract
The use of 2-hydroxypropyl-beta-cyclodextrin has made it possible to prepare stable aqueous solutions of cholesterol, 26-hydroxycholesterol, 7 alpha-hydroxycholesterol, and monohydroxy bile acids such as lithocholic and 3 beta-hydroxy-5-cholenoic acids. These solutions are suitable for cell culture studies and for parenteral administration to animals.
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