Shifted from Wnt to Hedgehog signaling pathways
- PMID: 15694333
- DOI: 10.1016/j.molcel.2005.01.009
Shifted from Wnt to Hedgehog signaling pathways
Abstract
Two papers in recent issue of Developmental Cell (Glise et al. 2005; Gorfinkiel et al. 2005) have shown that Shifted, a Drosophila ortholog of Wnt Inhibitory Factor (WIF), modulates the distribution of Hedgehog protein in the wing imaginal disc through a Wnt-independent mechanism.
Comment on
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The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog.Dev Cell. 2005 Feb;8(2):241-53. doi: 10.1016/j.devcel.2004.12.018. Dev Cell. 2005. PMID: 15691765
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Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog.Dev Cell. 2005 Feb;8(2):255-66. doi: 10.1016/j.devcel.2005.01.003. Dev Cell. 2005. PMID: 15691766
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